本院主辦第十四屆國際綠色永續生物科技研討會

本院蘭宜錚教授於2024年1月26-27日 辦理2024 第十四屆國際綠色永續生物科技研討會。

綠色永續生物科技研發團隊,其成立宗旨為致力發展綠色永續生物科技,「綠色永續生物科技」為利用生物體(含動物,植物及微生物的細胞)來生產有用的物質或製程的改進、生物特性的改良、降低成本及創新物種的科學技術,進行對醫學、環境、農業食糧等不同範疇提出新技術與貢獻。近年更朝著降低汙染及對自然環境無害的方向發展,主要內容為能源和環境技術的研究開發,其中特別指出綠色化學就是化學與永續發展的結合,其方向發展應符合改善人類健康和保護生態環境的要求。強調生物科技與產業應用的相關性,將「學術」與「產學結合」,加速「生物科技產業化」與「生物產業科技化」,以培養兼具「生物科技」和「產業應用」專業能力之人才。

本次研討會將同時辦理第七屆綠色永續盃啤酒競賽,為愛好啤酒的夥伴們,提供一個競賽與交流的機會。

活動網址:https://sites.google.com/view/2024gsbs

Holothurian triterpene glycoside cucumarioside A2-2 induces macrophages activation and polarization in cancer immunotherapy

王雲銘教授研究團隊發表研究成果於 Cancer Cell International

連結網址:https://pubmed.ncbi.nlm.nih.gov/38001420/

Abstract

Background: Despite intensive developments of adoptive T cell and NK cell therapies, the efficacy against solid tumors remains elusive. Our study demonstrates that macrophage-based cell therapy could be a potent therapeutic option against solid tumors.

Methods: To this end, we determine the effect of a natural triterpene glycoside, cucumarioside A2-2 (CA2-2), on the polarization of mouse macrophages into the M1 phenotype, and explore the antitumor activity of the polarized macrophage. The polarization of CA2-2-pretreated macrophages was analyzed by flow cytometry and confocal imaging. The anti-cancer activity of CA2-2 macrophages was evaluated against 4T1 breast cancer cells and EAC cells in vitro and syngeneic mouse model in vivo.

Results: Incubation of murine macrophages with CA2-2 led to polarization into the M1 phenotype, and the CA2-2-pretreated macrophages could selectively target and kill various types of cancer in vitro. Notably, loading near-infrared (NIR) fluorochrome-labeled nanoparticles, MnMEIO-mPEG-CyTE777, into macrophages substantiated that M1 macrophages can target and penetrate tumor tissues in vivo efficiently.

Conclusion: In this study, CA2-2-polarized M1 macrophages significantly attenuated tumor growth and prolonged mice survival in the syngeneic mouse models. Therefore, ex vivo CA2-2 activation of mouse macrophages can serve as a useful model for subsequent antitumor cellular immunotherapy developments.

Keywords: Anticancer; Cucumarioside A2-2; Holothurian triterpene glycoside; Immunotherapy; M1 macrophage.

國立陽明交通大學113年度碩博士班甄試入學新生座談會暨備取生報到注意事項

1.只要有備取名額釋放出來,我們會儘速於生科院網頁通知備取公告https://ceb.nycu.edu.tw/,也會寄送E-mail通知您。

2.本院謹訂於112125()上午10:00舉辦新生座談會並開放各實驗室參訪(中午備有餐點),非常歡迎備取生也參與當天座談會,一則可讓備取生提前瞭解可能遞補之機會,再則也可使將來遞補之備取生瞭解各位老師實驗室研究情形。

3.系(所)聯絡方式,電話:03-5729287、傳真:03-5729288

生物科技學院113學年新生座談會

時間:112年12月5日(星期二)

09:30–10:00正取生報到(地點:賢齊館310室)

10:00–10:30師生介紹(地點:賢齊館310室)

10:30–12:00參訪實驗室

12:00–13:00午餐(賢齊館310室)

13:00–16:00  參訪實驗室

碩士班甄試榜單https://sr2.aa.nycu.edu.tw/action.aspx?id=49722893-d200-4f70-8dd4-48280c702761

博士班甄試榜單https://sr2.aa.nycu.edu.tw/action.aspx?id=a48563db-9f4f-49ca-9036-adb06a522259

國立陽明交通大學113年度碩博士班甄試入學新生座談會暨正取生報到注意事項

國立陽明交通大學113年度碩博士班甄試入學新生座談會暨正取生報到注意事項

1.請正取生親自攜身分證正本、歷年成績單、畢業證書正本,請於112年12月5日(星期二)上午九時三十分前,至博愛校區賢齊館310室辦理報到手續,逾時未報到者,以放棄錄取資格論。(報到時須繳驗學歷(力)證件,應屆畢業生尚未領取畢業證書者,可填寫切結書辦理報到。)另在職生須附上在職證明書正本。

2.本院謹訂於112年12月5日(二)上午10:00舉辦新生座談會並開放各實驗室參訪(中午備有餐點),歡迎正、備取生踴躍參加。

生物科技學院113學年新生座談會

時間:112年12月5日(星期二)

09:30–10:00正取生報到(地點:賢齊館310室)

10:00–10:30師生介紹(地點:賢齊館310室)

10:30–12:00參訪實驗室

12:00–13:00午餐(賢齊館310室)

13:00–16:00參訪實驗室

3.錄取系(所)聯絡方式,電話:03-5729287、傳真:03-5729288

4.切結書

5.放棄聲明書

6.二月入學申請書及學位證書切結書

碩士班甄試榜單https://sr2.aa.nycu.edu.tw/action.aspx?id=49722893-d200-4f70-8dd4-48280c702761

博士班甄試榜單https://sr2.aa.nycu.edu.tw/action.aspx?id=a48563db-9f4f-49ca-9036-adb06a522259

Faculty Recruitment for College of Engineering Bioscience, National Yang Ming Chiao Tung University

Faculty Recruitment for College of Engineering Bioscience, National Yang Ming Chiao Tung University

 

The College of Engineering Bioscience (CEB, former College of Biological Science & Technology) at National Yang Ming Chiao Tung University (NYCU) functions as one entity and is composed of Department of Biological Science and Technology (DBT), Institute of Molecular Medicine and Bioengineering (IMB), as well as Institute of Bioinformatics and Systems Biology (IBS). CEB aims to address the current global challenges and construct a healthy, affordable, and sustainable society through the concepts and approaches of engineering bioscience: linking biotechnology, ICT, and computational biology from the molecular level to study fields such as precision medicine, translational engineering, and sustainable technology. CEB is the pioneer in NYCU at the interface of biology-chemistry, -physics, and -engineering. As such, CEB has numerous outstanding achievements in fields of bioelectronics and biosensing, bioinformatics, biomaterials, tissue engineering, microbial engineering, synthetic biology, structural biology, and neurotechnology.

 

Faculty positions available:

Professor, Associate Professor, and Assistant Professor

 

Application requirements:

Applicant should share a similar vision and goal as CEB and has an outstanding record in cutting edge research and teaching at undergraduate and graduate levels. The candidates we are looking for should have a research expertise in (alphabetic order) bio-big data & AI, bioelectronics and biosensing, biomaterials, cell therapy, computational biology, computational chemistry, metabolomics, microbiome, molecular imaging, organoid and tissue engineering, smart medicine, structural biology, sustainable technology, synthetic biology, or any other related disciplines.

In addition, successful candidates will be required to teach courses in English for the first three years of her or his appointment.

      

Deadline for application:

Application submission process will end on December 5th, 2023.

 

Application package should include:

  • Cover letter
  • Curriculum Vitae
  • Publication list and reprint copies of representative publications
  • Research & Teaching plans
  • Three reference letters sent directly by external referees
  • Estimated laboratory start-up budget and instrumentation needs

 

Applications should be sent to the Dr. Eric Hwang (Director of IMB) and cc. Ms. Sunny Kuo through e-mail. Their contact information is listed below:

 

Dr. Eric Hwang (hwangeric@nycu.edu.tw)

Ms. Sunny Kuo (sunny@nycu.edu.tw)

Phone: (+886)-3-5712121 extension 56937 (Ms. Kuo)

CEB webpage: https://ceb.nycu.edu.tw/

 

國立陽明交通大學工程生物科學院徵聘教師啟事

國立陽明交通大學工程生物科學院徵聘教師啟事

 

  • 工程生物科學院(原生物科技學院,下稱本院)由生物科技學系、分子醫學與生物工程研究所、生物資訊及系統生物研究所組成,本院以工程生物科學(Engineering Bioscience)從分子層次鏈結生物科技、ICT與計算生物,發展精準醫藥、轉譯工程及永續科技等領域,以建立健康、幸福、及永續的未來。本院在陽明交通大學立足於化學、物理、工程等尖端科技與生物科學的界面,以跨領域模式聯通基礎科學與產業應用,在生物電子、生物資訊、生醫材料、組織工程、微生物工程、合成生物、結構生物、與神經科技等領域成果豐碩。

  • 師資需求名額:數名。

  • 應徵職位:教授、副教授、助理教授。

  • 應徵資格:

  • 強烈認同本院發展理念與願景,對卓越研究與教學有熱情之生物科技與工程相關領域人才(包含但不限於生物電子、生醫材料、類器官與組織工程、細胞治療、生物大數據AI、計算生物、計算化學、代謝體學、微生物基因體學、合成生物、分子生醫影像、結構生物、永續科技、智慧醫療)皆歡迎申請。

  • 應徵人需有上述或相關領域博士學位

  • 應徵條件:新進教師前三年需以英語授課

  • 應徵截止日期:應徵資料將於2023/12/05截止收件

  • 應提送資料:(必須提供電子檔資料)

          (1)應徵意願書(Cover Letter)

         (2)個人資料(Curriculum Vitae)

         (3)著作清單及代表性論文抽印本

        (4)研究及教學計畫書

        (5)推薦函三封

        (6)實驗室成立預算與設備需求表

  • 應徵方法:
    將上述資料以e-mail寄送至分子醫學與生物工程研究所黃兆祺所長並副本至郭淑卿小姐,相關聯絡資訊如下:

黃兆祺所長(hwangeric@nycu.edu.tw
郭淑卿小姐(sunny@nycu.edu.tw
Tel:+886-3-5712121轉56937 (郭小姐)
網址:https://ceb.nycu.edu.tw/

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